[Emmajane ODonoghue]

Hi Michael
The WHO address came up as page not found.
Any chance you may be able to check same?
Thanks
Emmajane

Emmajane O’Donoghue

Infection Control Consultant
HICMR Pty Ltd
(Healthcare Infection Control Management Resources)
Level 1, 123 Camberwell Road, Hawthorn East 3123
Ph: (03) 98119923 Fax: (03) 98824534
National pager number: 1300-657-359
http://www.hicmr.com.au

—–Original Message—–
From: ACIPC Infexion Connexion [mailto:AICALIST@AICALIST.ORG.AU] On Behalf Of Michael Wishart
Sent: Saturday, 6 April 2013 10:47
To: AICALIST@AICALIST.ORG.AU
Subject: H7N9 influenza

[Forwarded on behalf of Claire Boardman – Moderator]
>
> Information for clinicians
>
> As you’d be aware, human cases of H7N9 influenza has been reported in
> China. Some information for clinicians (received from Dr Gary Lum at
> Office of Health Protection and summarized with permission), current
> as of Friday 5 April.
>
> 1. The number of confirmed patients is 11, including 5 fatalities.
>
> 2. There continues to be no evidence of human-to-human transmission
> and no epidemiological links between patients have been found.
>
> 3. All the patients detected to date have been seriously unwell.
>
> 4. Cases have been clustered in the central eastern provinces (3
> Shanghai; 1 Anhiu; 4 Jiangning and 3 Zhejiang). These are the
> provinces around the cities of Shanghai and Nanjing.
>
> 5. Analyses indicate that this virus is resistant to adamantanes but
> susceptible to oseltamivir.
>
> 6. This virus is subtyped as LPAI (for birds) H7N9 and appears to be
> an assortment of 3 avian viruses; the first 3 strains have been
> sequenced and appear to be closely related genetically.
>
> Testing
>
> PCR protocols have been developed and web-based publication is
> planned. Export of the virus to allow validation is also planned.
> Testing of suspected cases in Australia should be performed in
> consultation with jurisdictional public health units and reference
> laboratories.
>
> Further information for clinicians is being developed by CDNA.
>
> Historically
>
> No previous cases of H7 in humans have been reported in China (or
> Asia) prior to these cases
>
> Infection with H7 viruses is rare in humans, but viruses from both
> lineages (North American and Eurasian) have caused infection
> previously. Observed symptoms include conjunctivitis and mild
> respiratory symptoms. One fatal case (pneumonia) with HPAI H7N7 was
> reported in the Netherlands in 2003.
>
> Most human cases of H7 have been linked to occupational exposure (i.e.
> contact with poultry or laboratory exposure)
>
> The virus appears resistant to amantanes (e.g., amantadine) and
> susceptible to neurominidase inhibitors (oseltamivir and zanamivir).
>
> Further information is also available on the WHO website:
> http://www.who.int/influenza/human_animal_interface/faq_H7N9/en/index.
> html
>
> Allen
>
> —
> Allen Cheng
> Associate Professor in Infectious Diseases Epidemiology Department of
> Epidemiology and Preventive Medicine Monash University
>
> Infectious Diseases Physician
> Alfred Hospital
>
> Honorary Principal Research Fellow
> Menzies School of Health Research
>

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