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RE; Alcohol swab before injections

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  • #69873
    Franciska Ferreira
    Participant

    Author:
    Franciska Ferreira

    Position:
    Infection Prevention & Control/ Wound Ma

    Organisation:
    Burnside Hospital

    State:

    Hi All,

    There is still an ongoing debate whether we should use an alcohol swab before administering clexane, vaccines and insulin. Any ideas please?
    I know the latest practice in regards administering clexane is to “not swab”.

    I just want to advise my team from a infection control point of view with facts to stand on.

    Kind Regards

    Franciska Ferreira
    INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT
    Burnside War Memorial Hospital
    120 Kensington Road, Toorak Gardens, SA 5056
    t: 08 8202 7222 f: 08 8407 8573 e: fferreira@burnsidehospital.asn.au

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    #69875
    Rebecca O’Donnell
    Participant

    Author:
    Rebecca O’Donnell

    Position:

    Organisation:

    State:

    Hi Franciska,

    The Australian Immunisation Handbook 9th states 1.4.4 page 43 “provided the skin is visibly clean” no swabbing is required. If need be using an alcohol wipe is to be used, allow drying time before administering vaccination.

    I am not aware of any other recommendations for skin preparation for IM / SC route.

    Regards,

    Rebecca O’Donnell | Infection Prevention and Control Co-ordinator
    St Vincent’s Hospital Toowoomba | 22-36 Scott Street TOOWOOMBA 4350
    T 07 4690 4042 | F 07 46904400
    E rebecca.o’donnell@stvincents.org.au | W http://www.stvincents.org.au

    P Please consider the environment before printing this email.
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    Hi All,

    There is still an ongoing debate whether we should use an alcohol swab before administering clexane, vaccines and insulin. Any ideas please?
    I know the latest practice in regards administering clexane is to “not swab”.

    I just want to advise my team from a infection control point of view with facts to stand on.

    Kind Regards

    Franciska Ferreira
    INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT
    Burnside War Memorial Hospital
    120 Kensington Road, Toorak Gardens, SA 5056
    t: 08 8202 7222 f: 08 8407 8573 e: fferreira@burnsidehospital.asn.au

    ________________________________
    This email is intended only for the use of the individual or entity named above and may contain information that is confidential and privileged. If you are not the intended recipient, you are hereby notified that any dissemination, distribution or copying of this email is strictly prohibited. If you receive this email in error, could you please notify us by return email and delete it and any attachments from your system. Even though this message is scanned no representation is made that this email or any attachments are free of viruses or other defects. Virus scanning is recommended and is the responsibility of the recipient.

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    WARNING : This email contains information, which is CONFIDENTIAL, and that maybe subject to LEGAL PRIVILEGE. This e-mail and any attachments to it (the “Communication”) is confidential and is for the use only of the intended recipient, and may not duplicated or used by any other party without the express consent of the sender. The Communication may contain copyright material of St Vincent’s Health & Aged Care(“SVHAC”), or any of its related entities or of third parties. If you are not the intended recipient of the Communication, please notify the sender immediately by return e-mail, delete the Communication, and do not read, copy, print, retransmit, store or act in reliance on the Communication. Any views expressed in the Communication are those of the individual sender only, unless expressly stated to be those of SVHAC. SVHAC does not guarantee the integrity of the Communication, or that it is free from errors, viruses or interference. Thank-you.

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    #69877
    Pethrick, Cassie
    Participant

    Author:
    Pethrick, Cassie

    Position:

    Organisation:

    State:

    Hi Franciska
    The immunization guidleines reflect that swabbing of skin is not
    recommended for vaccines unless the injectable area is dirty – see link
    http://www.immunise.health.gov.au/internet/immunise/publishing.nsf/Conte
    nt/Handbook-home
    Section 1.4.4 – Provided the skin is visibly clean, there is no need to
    wipe it with an antiseptic (eg. alcohol wipe).3,4 If the immunisation
    service provider decides to clean the skin, or if the skin is visibly
    not clean, alcohol and other disinfecting agents must be allowed to dry
    before vaccine injection (otherwise there may be some increased
    injection pain).

    Hope that helps
    Thanks Cassie
    Cassie Pethrick
    OSH Consultant
    Moore House, Brockway Road
    Mt Claremont WA 6010

    ________________________________

    Behalf Of Franciska Ferreira

    Hi All,

    There is still an ongoing debate whether we should use an alcohol swab
    before administering clexane, vaccines and insulin. Any ideas please?

    I know the latest practice in regards administering clexane is to “not
    swab”.

    I just want to advise my team from a infection control point of view
    with facts to stand on.

    Kind Regards

    Franciska Ferreira

    INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT

    Burnside War Memorial Hospital

    120 Kensington Road, Toorak Gardens, SA 5056

    t: 08 8202 7222 f: 08 8407 8573 e: fferreira@burnsidehospital.asn.au

    ________________________________

    This email is intended only for the use of the individual or entity
    named above and may contain information that is confidential and
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    please notify us by return email and delete it and any attachments from
    your system. Even though this message is scanned no representation is
    made that this email or any attachments are free of viruses or other
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    recipient.

    ______________________________________________________________________
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    service.
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    #69876
    Matthias Maiwald (KKH)
    Participant

    Author:
    Matthias Maiwald (KKH)

    Position:

    Organisation:

    State:

    Dear Franciska,

    Not sure about clexane and insulin (s.c. injections), but I have looked in some detail into the current Australian recommendations concerning vaccinations. Most vaccinations are i.m. injections, which are biologically quite different from s.c. injections and also from venipuncture. The official recommendation by the Australian Immunisation Handbook is not to swab (so if you follow that, you are following official recommendations), and only to swab if the injection area is visibly dirty, but the problem is that these recommendation are severely misguided and intellectually flawed.

    (1) Much of it is based on a short 2001 article in the MJA, examining a few hundred s.c. injections and venipunctures, and concluding that swabbing for ANY type of injection is not necessary, including i.m. injections. There are two fatal flaws with this assumption. (a) The article did not examine even a single i.m. injection and made conclusions pertaining to these (which is inconsistent with the principles of evidence-based medicine, which the article purported to adhere to), and (b) the natural infection rate after i.m. injections is very low, estimated to be in the range of 1:5000 to 1:10000 or less (which is reassuring), but if you study a smaller population than is needed to capture the natural incidence of an event, then you cannot make conclusions that the intervention has no effect on the occurrence of the event.

    (2) The recommendation to swab only if visibly soiled is not justified either, because microorganisms are invisible, and implementing this as a cutoff between swabbing and non-swabbing is arbitrary without a scientific base or evidence base. Imagine you sit in front of a patient with a darker skin colour and want to give an injection. When would you be confident that the skin is NOT visibly dirty?

    In summary, if you don’t swab, you are consistent with the guidelines, but the guidelines are seriously flawed (at least you won’t be responsible then). It is certainly reassuring that the natural infection rate is very low, and statistically you are unlikely (but it is possible) to see any adverse event. It is clear that i.m. injections and other types of injections are biologically and clinically different and bear a different infection risk. Also, the deeper an injection is, the more complicated infections can get (examples on the complicated end are joint injections, corticosteroid injections, or more complicated injections).

    Best regards, Matthias.


    Matthias Maiwald, MD, FRCPA
    Consultant in Microbiology
    Adj. Assoc. Prof., Natl. Univ. Singapore
    Department of Pathology and Laboratory Medicine
    KK Women’s and Children’s Hospital
    100 Bukit Timah Road
    Singapore 229899
    Tel. +65 6394 8725 (Office)
    Tel. +65 6394 1389 (Laboratory)
    Fax +65 6394 1387

    Hi All,

    There is still an ongoing debate whether we should use an alcohol swab before administering clexane, vaccines and insulin. Any ideas please?
    I know the latest practice in regards administering clexane is to “not swab”.

    I just want to advise my team from a infection control point of view with facts to stand on.

    Kind Regards

    Franciska Ferreira
    INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT
    Burnside War Memorial Hospital
    120 Kensington Road, Toorak Gardens, SA 5056
    t: 08 8202 7222 f: 08 8407 8573 e: fferreira@burnsidehospital.asn.au

    ________________________________
    This email is intended only for the use of the individual or entity named above and may contain information that is confidential and privileged. If you are not the intended recipient, you are hereby notified that any dissemination, distribution or copying of this email is strictly prohibited. If you receive this email in error, could you please notify us by return email and delete it and any attachments from your system. Even though this message is scanned no representation is made that this email or any attachments are free of viruses or other defects. Virus scanning is recommended and is the responsibility of the recipient.

    ______________________________________________________________________
    This email has been scanned by the Symantec Email Security.cloud service.
    For more information please visit http://www.symanteccloud.com
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    [cid:kkh2ebe.gif]kkh

    ________________________________
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    #69878
    Claire Rickard
    Participant

    Author:
    Claire Rickard

    Position:

    Organisation:

    State:

    I completely agree with you Matthias.

    With injections into IV ports we are now encouraged to “scrub the hub” for
    30 seconds with either isopropyl alchol or alcoholic chlrohexidine etc!

    Yet for the skin, which is nice and warm and moist – capable of supporting
    much higher microbe counts than a dry cool rubber bung, we use
    nothing…bizarre!!!

    Best regards, Claire

    *Professor Claire Rickard RN PhD*

    c.rickard@griffith.edu.au | +61 7 3735 6460 | Skype: clairexm1 | Twitter:
    IVAD_Research | Intravascular Access Device Research Group | NHMRC Centre
    of Research Excellence in Nursing | Centre for Health Practice
    Innovation | Griffith
    Health Institute | Griffith University

    Visiting Scholar: Royal Brisbane & Women’s Hospital | Princess Alexandra
    Hospital | The Prince Charles Hospital

    P.S. Research frequently takes me off campus. Please contact Jenny Chan,
    School Secretary 3735 5406 or *j.chan@griffith.edu.au*
    with any urgent enquiries.

    On 25 March 2013 11:29, Matthias Maiwald (KKH)
    wrote:

    > Dear Franciska, ****
    >
    > ** **
    >
    > Not sure about clexane and insulin (s.c. injections), but I have looked in
    > some detail into the current Australian recommendations concerning
    > vaccinations. Most vaccinations are i.m. injections, which are biologically
    > quite different from s.c. injections and also from venipuncture. The
    > official recommendation by the Australian Immunisation Handbook is not to
    > swab (so if you follow that, you are following official recommendations),
    > and only to swab if the injection area is visibly dirty, but the problem is
    > that these recommendation are severely misguided and intellectually flawed.
    > ****
    >
    > ** **
    >
    > (1) Much of it is based on a short 2001 article in the MJA, examining a
    > few hundred s.c. injections and venipunctures, and concluding that swabbing
    > for ANY type of injection is not necessary, including i.m. injections.
    > There are two fatal flaws with this assumption. (a) The article did not
    > examine even a single i.m. injection and made conclusions pertaining to
    > these (which is inconsistent with the principles of evidence-based
    > medicine, which the article purported to adhere to), and (b) the natural
    > infection rate after i.m. injections is very low, estimated to be in the
    > range of 1:5000 to 1:10000 or less (which is reassuring), but if you study
    > a smaller population than is needed to capture the natural incidence of an
    > event, then you cannot make conclusions that the intervention has no effect
    > on the occurrence of the event. ****
    >
    > ** **
    >
    > (2) The recommendation to swab only if visibly soiled is not justified
    > either, because microorganisms are invisible, and implementing this as a
    > cutoff between swabbing and non-swabbing is arbitrary without a scientific
    > base or evidence base. Imagine you sit in front of a patient with a darker
    > skin colour and want to give an injection. When would you be confident that
    > the skin is NOT visibly dirty? ****
    >
    > ** **
    >
    > In summary, if you don’t swab, you are consistent with the guidelines, but
    > the guidelines are seriously flawed (at least you won’t be responsible
    > then). It is certainly reassuring that the natural infection rate is very
    > low, and statistically you are unlikely (but it is possible) to see any
    > adverse event. It is clear that i.m. injections and other types of
    > injections are biologically and clinically different and bear a different
    > infection risk. Also, the deeper an injection is, the more complicated
    > infections can get (examples on the complicated end are joint injections,
    > corticosteroid injections, or more complicated injections). ****
    >
    > ** **
    >
    > Best regards, Matthias. ****
    >
    > ** **
    >
    > — ****
    >
    > Matthias Maiwald, MD, FRCPA ** **
    >
    > Consultant in Microbiology ** **
    >
    > Adj. Assoc. Prof., Natl. Univ. Singapore ****
    >
    > Department of Pathology and Laboratory Medicine ****
    >
    > KK Women’s and Children’s Hospital ****
    >
    > 100 Bukit Timah Road ****
    >
    > Singapore 229899 ****
    >
    > Tel. +65 6394 8725 (Office) ** **
    >
    > Tel. +65 6394 1389 (Laboratory) ** **
    >
    > Fax +65 6394 1387****
    >
    > ** **
    >
    > *From:* ACIPC Infexion Connexion [mailto:AICALIST@AICALIST.ORG.AU] *On
    > Behalf Of *Franciska Ferreira
    > *Sent:* Monday, 25 March, 2013 8:54 AM
    > *To:* AICALIST@AICALIST.ORG.AU
    > *Subject:* RE; Alcohol swab before injections****
    >
    > ** **
    >
    > Hi All,****
    >
    > ** **
    >
    > There is still an ongoing debate whether we should use an alcohol swab
    > before administering clexane, vaccines and insulin. Any ideas please?****
    >
    > I know the latest practice in regards administering clexane is to not
    > swab.****
    >
    > ** **
    >
    > I just want to advise my team from a infection control point of view with
    > facts to stand on.****
    >
    > ** **
    >
    > Kind Regards****
    >
    > ** **
    >
    > *Franciska Ferreira*
    >
    > *INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT*
    >
    > Burnside War Memorial Hospital****
    >
    > 120 Kensington Road, Toorak Gardens, SA 5056****
    >
    > *t:** *08 8202 7222 *f:** *08 8407 8573 e:
    > fferreira@burnsidehospital.asn.au****
    >
    > ** **
    >
    > ** **
    > ——————————
    >
    > This email is intended only for the use of the individual or entity named
    > above and may contain information that is confidential and privileged. If
    > you are not the intended recipient, you are hereby notified that any
    > dissemination, distribution or copying of this email is strictly
    > prohibited. If you receive this email in error, could you please notify us
    > by return email and delete it and any attachments from your system. Even
    > though this message is scanned no representation is made that this email or
    > any attachments are free of viruses or other defects. Virus scanning is
    > recommended and is the responsibility of the recipient.
    >
    > ______________________________________________________________________
    > This email has been scanned by the Symantec Email Security.cloud service.
    > For more information please visit http://www.symanteccloud.com
    > ______________________________________________________________________****
    >
    > Messages posted to this list are solely the opinion of the authors, and do
    > not represent the opinion of ACIPC. ****
    >
    > Archive of all messages are available at http://aicalist.org.au/archives- registration and login required.
    > ****
    >
    > Replies to this message will be directed back to the list. To create a new
    > message send an email to aicalist@aicalist.org.au ****
    >
    > To send a message to the list administrator send an email to
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    >
    > You can unsubscribe from this list be sending ‘signoff aicalist’ (without
    > the quotes) to listserv@aicalist.org.au ****
    >
    >
    >
    > kkh
    >
    > ——————————
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    > addressee. If you are not the intended recipient, please do not print,
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    > and delete all copies of this e-mail and the attachments.
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    >
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    > do not represent the opinion of ACIPC.
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    #69879
    Tim Spencer
    Participant

    Author:
    Tim Spencer

    Position:

    Organisation:

    State:

    Thanks for a very informed and well-structured reply Mathias.

    I totally agree.

    Timothy R. Spencer, RN, APN, DipAppSci, Bach.Health, ICCert.
    Clinical Nurse Consultant, Central Venous Access & Parenteral Nutrition
    Service

    Conjoint Lecturer, South West Sydney Clinical School | Faculty of
    Medicine | University of NSW
    Dept of Intensive Care, Level 2, Clinical Building, Liverpool Hospital,
    Elizabeth Street, Liverpool, 2170, NSW, Australia
    Tel (+61) 2 8738 3603 | Fax (+61) 2 8738 3551 | Mob +61 (0)409 463 428 |
    Tim.Spencer@sswahs.nsw.gov.au | Timothy.Spencer@unsw.edu.au

    Behalf Of Matthias Maiwald (KKH)

    Dear Franciska,

    Not sure about clexane and insulin (s.c. injections), but I have looked
    in some detail into the current Australian recommendations concerning
    vaccinations. Most vaccinations are i.m. injections, which are
    biologically quite different from s.c. injections and also from
    venipuncture. The official recommendation by the Australian Immunisation
    Handbook is not to swab (so if you follow that, you are following
    official recommendations), and only to swab if the injection area is
    visibly dirty, but the problem is that these recommendation are severely
    misguided and intellectually flawed.

    (1) Much of it is based on a short 2001 article in the MJA, examining a
    few hundred s.c. injections and venipunctures, and concluding that
    swabbing for ANY type of injection is not necessary, including i.m.
    injections. There are two fatal flaws with this assumption. (a) The
    article did not examine even a single i.m. injection and made
    conclusions pertaining to these (which is inconsistent with the
    principles of evidence-based medicine, which the article purported to
    adhere to), and (b) the natural infection rate after i.m. injections is
    very low, estimated to be in the range of 1:5000 to 1:10000 or less
    (which is reassuring), but if you study a smaller population than is
    needed to capture the natural incidence of an event, then you cannot
    make conclusions that the intervention has no effect on the occurrence
    of the event.

    (2) The recommendation to swab only if visibly soiled is not justified
    either, because microorganisms are invisible, and implementing this as a
    cutoff between swabbing and non-swabbing is arbitrary without a
    scientific base or evidence base. Imagine you sit in front of a patient
    with a darker skin colour and want to give an injection. When would you
    be confident that the skin is NOT visibly dirty?

    In summary, if you don’t swab, you are consistent with the guidelines,
    but the guidelines are seriously flawed (at least you won’t be
    responsible then). It is certainly reassuring that the natural infection
    rate is very low, and statistically you are unlikely (but it is
    possible) to see any adverse event. It is clear that i.m. injections and
    other types of injections are biologically and clinically different and
    bear a different infection risk. Also, the deeper an injection is, the
    more complicated infections can get (examples on the complicated end are
    joint injections, corticosteroid injections, or more complicated
    injections).

    Best regards, Matthias.

    Matthias Maiwald, MD, FRCPA

    Consultant in Microbiology

    Adj. Assoc. Prof., Natl. Univ. Singapore

    Department of Pathology and Laboratory Medicine

    KK Women’s and Children’s Hospital

    100 Bukit Timah Road

    Singapore 229899

    Tel. +65 6394 8725 (Office)

    Tel. +65 6394 1389 (Laboratory)

    Fax +65 6394 1387

    Behalf Of Franciska Ferreira

    Hi All,

    There is still an ongoing debate whether we should use an alcohol swab
    before administering clexane, vaccines and insulin. Any ideas please?

    I know the latest practice in regards administering clexane is to “not
    swab”.

    I just want to advise my team from a infection control point of view
    with facts to stand on.

    Kind Regards

    Franciska Ferreira

    INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT

    Burnside War Memorial Hospital

    120 Kensington Road, Toorak Gardens, SA 5056

    t: 08 8202 7222 f: 08 8407 8573 e: fferreira@burnsidehospital.asn.au

    ________________________________

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    kkh

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    #69884
    Matthias Maiwald (KKH)
    Participant

    Author:
    Matthias Maiwald (KKH)

    Position:

    Organisation:

    State:

    Actually, although this is strictly unproven (only anecdotal), direct access to a blood vessel and then removing the needle, such as in venipuncture or i.v. injection, presumably has a lower risk of infection than injecting into tissue, because in tissue it takes a while for defense cells to reach it. What makes vascular catheters and i.v. cannulas (that stay in) more problematic than clean, one-off access into blood vessels is that you have (a) hardware that stays in place, and (b) a continuing skin breach over several days, from which the organisms can enter.

    From the 1999 CDC surgical site infection guideline, the conceptual framework for the risk of surgical site infections is:

    Dose of bacterial contamination x virulence
    ——————————————————- risk of surgical site infection
    resistance of the host patient

    (Hope the display of the equation comes across OK).

    This would similarly apply to injections, although all the parameters involved are different from those in surgery.

    If you look at a recent article from MJA:

    http://www.ncbi.nlm.nih.gov/pubmed/23496408

    even though the inoculum in the injection and the virulence was probably very (!) low, there were two factors that decreased the host resistance, (a) prosthetic joint (hardware) in place, and (b) a large volume (8 mL) of injected fluid, which makes drainage of the fluid from the injected site difficult, and therefore a very small inoculum can cause an infection.

    M.


    Matthias Maiwald, MD, FRCPA
    Consultant in Microbiology
    Adj. Assoc. Prof., Natl. Univ. Singapore
    Department of Pathology and Laboratory Medicine
    KK Women’s and Children’s Hospital
    100 Bukit Timah Road
    Singapore 229899
    Tel. +65 6394 8725 (Office)
    Tel. +65 6394 1389 (Laboratory)
    Fax +65 6394 1387

    in fact, I have quite a nice bruise the size of a 5c piece after my flu needle, which bears out my theory that supposed IM injections can be exposed directly to the bloodstream quite nicely! (although I would rather they didn’t)

    Best regards, Claire

    Professor Claire Rickard RN PhD

    c.rickard@griffith.edu.au | +61 7 3735 6460 | Skype: clairexm1 | Twitter: IVAD_Research | Intravascular Access Device Research Group | NHMRC Centre of Research Excellence in Nursing | Centre for Health Practice Innovation | Griffith Health Institute | Griffith University

    Visiting Scholar: Royal Brisbane & Women’s Hospital | Princess Alexandra Hospital | The Prince Charles Hospital

    P.S. Research frequently takes me off campus. Please contact Jenny Chan, School Secretary 3735 5406 or j.chan@griffith.edu.au with any urgent enquiries.

    On 25 March 2013 12:48, Claire Rickard <c.rickard@griffith.edu.au> wrote:
    True enough Michael…although all sorts of tiny vessels lie within the subcutaneous and muscle tissue…who’s to say we are not injecting directly into some of these when we gve an IM/SC?

    As you say, better to err on the side of caution since the consequences are so catastrophic…as your cost-benefit analysis bears out 🙂

    Best regards, Claire

    Professor Claire Rickard RN PhD

    c.rickard@griffith.edu.au | +61 7 3735 6460 | Skype: clairexm1 | Twitter: IVAD_Research | Intravascular Access Device Research Group | NHMRC Centre of Research Excellence in Nursing | Centre for Health Practice Innovation | Griffith Health Institute | Griffith University

    Visiting Scholar: Royal Brisbane & Women’s Hospital | Princess Alexandra Hospital | The Prince Charles Hospital

    P.S. Research frequently takes me off campus. Please contact Jenny Chan, School Secretary 3735 5406 or j.chan@griffith.edu.au with any urgent enquiries.

    On 25 March 2013 12:17, Michael Wishart <Michael.Wishart@hsn.org.au> wrote:
    Hi Claire

    I, too, agree with Matthias, but I do not think your comparison with IV access is correct. Giving a sub-cut or IM injection has a much lesser risk of infective complications than any direct access to the blood stream (such as IV access or phlebotomy, for example). In my own practice I currently still use alcohol swabs prior to IM vaccination as it is quick, cheap and not worth the potential infective risk (which is yet to be well quantified as pointed out by Matthias).

    If patients are self-injecting (either sub-cut or IM), then the risk from auto-inoculation with their own flora may be even lower (viz self-catheterisation guidelines), so I would have no issues with teaching patients not to swab their own skin prior to a simple injection (as long as they were not directly injecting into a vein or device, though). The evidence supporting this is also pretty scant, though.

    Cheers
    Michael

    Michael Wishart
    CNC Infection Control
    Holy Spirit Northside Private Hospital
    627 Rode Road, Chermside, Qld 4032
    t: (07) 3326 3068 | f: (07) 3607 2226
    e: Michael.Wishart@hsn.org.au
    w:www.holyspiritnorthside.org.au
    Please consider the environment before printing this email

    I completely agree with you Matthias.

    With injections into IV ports we are now encouraged to “scrub the hub” for 30 seconds with either isopropyl alchol or alcoholic chlrohexidine etc!

    Yet for the skin, which is nice and warm and moist – capable of supporting much higher microbe counts than a dry cool rubber bung, we use nothing…bizarre!!!

    Best regards, Claire

    Professor Claire Rickard RN PhD

    c.rickard@griffith.edu.au | +61 7 3735 6460 | Skype: clairexm1 | Twitter: IVAD_Research | Intravascular Access Device Research Group | NHMRC Centre of Research Excellence in Nursing | Centre for Health Practice Innovation | Griffith Health Institute | Griffith University

    Visiting Scholar: Royal Brisbane & Women’s Hospital | Princess Alexandra Hospital | The Prince Charles Hospital

    P.S. Research frequently takes me off campus. Please contact Jenny Chan, School Secretary 3735 5406 or j.chan@griffith.edu.au with any urgent enquiries.

    On 25 March 2013 11:29, Matthias Maiwald (KKH) <matthias.maiwald@kkh.com.sg> wrote:
    Dear Franciska,

    Not sure about clexane and insulin (s.c. injections), but I have looked in some detail into the current Australian recommendations concerning vaccinations. Most vaccinations are i.m. injections, which are biologically quite different from s.c. injections and also from venipuncture. The official recommendation by the Australian Immunisation Handbook is not to swab (so if you follow that, you are following official recommendations), and only to swab if the injection area is visibly dirty, but the problem is that these recommendation are severely misguided and intellectually flawed.

    (1) Much of it is based on a short 2001 article in the MJA, examining a few hundred s.c. injections and venipunctures, and concluding that swabbing for ANY type of injection is not necessary, including i.m. injections. There are two fatal flaws with this assumption. (a) The article did not examine even a single i.m. injection and made conclusions pertaining to these (which is inconsistent with the principles of evidence-based medicine, which the article purported to adhere to), and (b) the natural infection rate after i.m. injections is very low, estimated to be in the range of 1:5000 to 1:10000 or less (which is reassuring), but if you study a smaller population than is needed to capture the natural incidence of an event, then you cannot make conclusions that the intervention has no effect on the occurrence of the event.

    (2) The recommendation to swab only if visibly soiled is not justified either, because microorganisms are invisible, and implementing this as a cutoff between swabbing and non-swabbing is arbitrary without a scientific base or evidence base. Imagine you sit in front of a patient with a darker skin colour and want to give an injection. When would you be confident that the skin is NOT visibly dirty?

    In summary, if you don’t swab, you are consistent with the guidelines, but the guidelines are seriously flawed (at least you won’t be responsible then). It is certainly reassuring that the natural infection rate is very low, and statistically you are unlikely (but it is possible) to see any adverse event. It is clear that i.m. injections and other types of injections are biologically and clinically different and bear a different infection risk. Also, the deeper an injection is, the more complicated infections can get (examples on the complicated end are joint injections, corticosteroid injections, or more complicated injections).

    Best regards, Matthias.


    Matthias Maiwald, MD, FRCPA
    Consultant in Microbiology
    Adj. Assoc. Prof., Natl. Univ. Singapore
    Department of Pathology and Laboratory Medicine
    KK Women’s and Children’s Hospital
    100 Bukit Timah Road
    Singapore 229899
    Tel. +65 6394 8725 (Office)
    Tel. +65 6394 1389 (Laboratory)
    Fax +65 6394 1387

    Hi All,

    There is still an ongoing debate whether we should use an alcohol swab before administering clexane, vaccines and insulin. Any ideas please?
    I know the latest practice in regards administering clexane is to “not swab”.

    I just want to advise my team from a infection control point of view with facts to stand on.

    Kind Regards

    Franciska Ferreira
    INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT
    Burnside War Memorial Hospital
    120 Kensington Road, Toorak Gardens, SA 5056
    t: 08 8202 7222 f: 08 8407 8573 e: fferreira@burnsidehospital.asn.au

    ________________________________
    This email is intended only for the use of the individual or entity named above and may contain information that is confidential and privileged. If you are not the intended recipient, you are hereby notified that any dissemination, distribution or copying of this email is strictly prohibited. If you receive this email in error, could you please notify us by return email and delete it and any attachments from your system. Even though this message is scanned no representation is made that this email or any attachments are free of viruses or other defects. Virus scanning is recommended and is the responsibility of the recipient.

    ______________________________________________________________________
    This email has been scanned by the Symantec Email Security.cloud service.
    For more information please visit http://www.symanteccloud.com
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    kkh

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    #69886
    Anonymous
    Inactive

    Author:
    Anonymous

    Position:

    Organisation:

    State:

    I cared for a patient who developed extensive cellulitis at IMI injection site and then went on to develop a spinal abscess.

    No doubt the rarest of rare complications, however, I continue to swab !

    Rebecca McCann Program Manager
    Healthcare Associated Infection Unit (HAIU)
    Communicable Disease Control Directorate Department of Health
    Grace Vaughan House
    227 Stubbs Terrace
    SHENTON PARK WA 6008
    T:08 9388 4859 M:0439 920 819 F:08 9388 4888
    E:rebecca.mccann@health.wa.gov.au

    The contents of this e-mail transmission are intended for the named recipients only and may contain confidential and/or privileged information. If you received this message in error, you must not copy, duplicate, forward, print or otherwise distribute any information contained herein, but must ensure that this e-mail is permanently deleted and advise the sender immediately.

    Actually, although this is strictly unproven (only anecdotal), direct access to a blood vessel and then removing the needle, such as in venipuncture or i.v. injection, presumably has a lower risk of infection than injecting into tissue, because in tissue it takes a while for defense cells to reach it. What makes vascular catheters and i.v. cannulas (that stay in) more problematic than clean, one-off access into blood vessels is that you have (a) hardware that stays in place, and (b) a continuing skin breach over several days, from which the organisms can enter.

    From the 1999 CDC surgical site infection guideline, the conceptual framework for the risk of surgical site infections is:

    Dose of bacterial contamination x virulence

    ——————————————————- risk of surgical site infection

    resistance of the host patient

    (Hope the display of the equation comes across OK).

    This would similarly apply to injections, although all the parameters involved are different from those in surgery.

    If you look at a recent article from MJA:

    http://www.ncbi.nlm.nih.gov/pubmed/23496408

    even though the inoculum in the injection and the virulence was probably very (!) low, there were two factors that decreased the host resistance, (a) prosthetic joint (hardware) in place, and (b) a large volume (8 mL) of injected fluid, which makes drainage of the fluid from the injected site difficult, and therefore a very small inoculum can cause an infection.

    M.

    Matthias Maiwald, MD, FRCPA

    Consultant in Microbiology

    Adj. Assoc. Prof., Natl. Univ. Singapore

    Department of Pathology and Laboratory Medicine

    KK Women’s and Children’s Hospital

    100 Bukit Timah Road

    Singapore 229899

    Tel. +65 6394 8725 (Office)

    Tel. +65 6394 1389 (Laboratory)

    Fax +65 6394 1387

    in fact, I have quite a nice bruise the size of a 5c piece after my flu needle, which bears out my theory that supposed IM injections can be exposed directly to the bloodstream quite nicely! (although I would rather they didn’t)

    Best regards, Claire

    Professor Claire Rickard RN PhD

    c.rickard@griffith.edu.au | +61 7 3735 6460 | Skype: clairexm1 | Twitter: IVAD_Research | Intravascular Access Device Research Group | NHMRC Centre of Research Excellence in Nursing | Centre for Health Practice Innovation | Griffith Health Institute | Griffith University

    Visiting Scholar: Royal Brisbane & Women’s Hospital | Princess Alexandra Hospital | The Prince Charles Hospital

    P.S. Research frequently takes me off campus. Please contact Jenny Chan, School Secretary 3735 5406 or j.chan@griffith.edu.au with any urgent enquiries.

    On 25 March 2013 12:48, Claire Rickard wrote:

    True enough Michael…although all sorts of tiny vessels lie within the subcutaneous and muscle tissue…who’s to say we are not injecting directly into some of these when we gve an IM/SC?

    As you say, better to err on the side of caution since the consequences are so catastrophic…as your cost-benefit analysis bears out 🙂

    Best regards, Claire

    Professor Claire Rickard RN PhD

    c.rickard@griffith.edu.au | +61 7 3735 6460 | Skype: clairexm1 | Twitter: IVAD_Research | Intravascular Access Device Research Group | NHMRC Centre of Research Excellence in Nursing | Centre for Health Practice Innovation | Griffith Health Institute | Griffith University

    Visiting Scholar: Royal Brisbane & Women’s Hospital | Princess Alexandra Hospital | The Prince Charles Hospital

    P.S. Research frequently takes me off campus. Please contact Jenny Chan, School Secretary 3735 5406 or j.chan@griffith.edu.au with any urgent enquiries.

    On 25 March 2013 12:17, Michael Wishart wrote:

    Hi Claire

    I, too, agree with Matthias, but I do not think your comparison with IV access is correct. Giving a sub-cut or IM injection has a much lesser risk of infective complications than any direct access to the blood stream (such as IV access or phlebotomy, for example). In my own practice I currently still use alcohol swabs prior to IM vaccination as it is quick, cheap and not worth the potential infective risk (which is yet to be well quantified as pointed out by Matthias).

    If patients are self-injecting (either sub-cut or IM), then the risk from auto-inoculation with their own flora may be even lower (viz self-catheterisation guidelines), so I would have no issues with teaching patients not to swab their own skin prior to a simple injection (as long as they were not directly injecting into a vein or device, though). The evidence supporting this is also pretty scant, though.

    Cheers

    Michael

    Michael Wishart

    CNC Infection Control

    Holy Spirit Northside Private Hospital

    627 Rode Road, Chermside, Qld 4032

    t: (07) 3326 3068 | f: (07) 3607 2226

    e: Michael.Wishart@hsn.org.au

    w:www.holyspiritnorthside.org.au

    Please consider the environment before printing this email

    I completely agree with you Matthias.

    With injections into IV ports we are now encouraged to “scrub the hub” for 30 seconds with either isopropyl alchol or alcoholic chlrohexidine etc!

    Yet for the skin, which is nice and warm and moist – capable of supporting much higher microbe counts than a dry cool rubber bung, we use nothing…bizarre!!!

    Best regards, Claire

    Professor Claire Rickard RN PhD

    c.rickard@griffith.edu.au | +61 7 3735 6460 | Skype: clairexm1 | Twitter: IVAD_Research | Intravascular Access Device Research Group | NHMRC Centre of Research Excellence in Nursing | Centre for Health Practice Innovation | Griffith Health Institute | Griffith University

    Visiting Scholar: Royal Brisbane & Women’s Hospital | Princess Alexandra Hospital | The Prince Charles Hospital

    P.S. Research frequently takes me off campus. Please contact Jenny Chan, School Secretary 3735 5406 or j.chan@griffith.edu.au with any urgent enquiries.

    On 25 March 2013 11:29, Matthias Maiwald (KKH) wrote:

    Dear Franciska,

    Not sure about clexane and insulin (s.c. injections), but I have looked in some detail into the current Australian recommendations concerning vaccinations. Most vaccinations are i.m. injections, which are biologically quite different from s.c. injections and also from venipuncture. The official recommendation by the Australian Immunisation Handbook is not to swab (so if you follow that, you are following official recommendations), and only to swab if the injection area is visibly dirty, but the problem is that these recommendation are severely misguided and intellectually flawed.

    (1) Much of it is based on a short 2001 article in the MJA, examining a few hundred s.c. injections and venipunctures, and concluding that swabbing for ANY type of injection is not necessary, including i.m. injections. There are two fatal flaws with this assumption. (a) The article did not examine even a single i.m. injection and made conclusions pertaining to these (which is inconsistent with the principles of evidence-based medicine, which the article purported to adhere to), and (b) the natural infection rate after i.m. injections is very low, estimated to be in the range of 1:5000 to 1:10000 or less (which is reassuring), but if you study a smaller population than is needed to capture the natural incidence of an event, then you cannot make conclusions that the intervention has no effect on the occurrence of the event.

    (2) The recommendation to swab only if visibly soiled is not justified either, because microorganisms are invisible, and implementing this as a cutoff between swabbing and non-swabbing is arbitrary without a scientific base or evidence base. Imagine you sit in front of a patient with a darker skin colour and want to give an injection. When would you be confident that the skin is NOT visibly dirty?

    In summary, if you don’t swab, you are consistent with the guidelines, but the guidelines are seriously flawed (at least you won’t be responsible then). It is certainly reassuring that the natural infection rate is very low, and statistically you are unlikely (but it is possible) to see any adverse event. It is clear that i.m. injections and other types of injections are biologically and clinically different and bear a different infection risk. Also, the deeper an injection is, the more complicated infections can get (examples on the complicated end are joint injections, corticosteroid injections, or more complicated injections).

    Best regards, Matthias.

    Matthias Maiwald, MD, FRCPA

    Consultant in Microbiology

    Adj. Assoc. Prof., Natl. Univ. Singapore

    Department of Pathology and Laboratory Medicine

    KK Women’s and Children’s Hospital

    100 Bukit Timah Road

    Singapore 229899

    Tel. +65 6394 8725 (Office)

    Tel. +65 6394 1389 (Laboratory)

    Fax +65 6394 1387

    Hi All,

    There is still an ongoing debate whether we should use an alcohol swab before administering clexane, vaccines and insulin. Any ideas please?

    I know the latest practice in regards administering clexane is to not swab.

    I just want to advise my team from a infection control point of view with facts to stand on.

    Kind Regards

    Franciska Ferreira

    INFECTION PREVENTION & CONTROL /WOUND MANAGEMENT CONSULTANT

    Burnside War Memorial Hospital

    120 Kensington Road, Toorak Gardens, SA 5056

    t: 08 8202 7222 f: 08 8407 8573 e: fferreira@burnsidehospital.asn.au

    ________________________________

    This email is intended only for the use of the individual or entity named above and may contain information that is confidential and privileged. If you are not the intended recipient, you are hereby notified that any dissemination, distribution or copying of this email is strictly prohibited. If you receive this email in error, could you please notify us by return email and delete it and any attachments from your system. Even though this message is scanned no representation is made that this email or any attachments are free of viruses or other defects. Virus scanning is recommended and is the responsibility of the recipient.

    ______________________________________________________________________
    This email has been scanned by the Symantec Email Security.cloud service.
    For more information please visit http://www.symanteccloud.com
    ______________________________________________________________________

    Messages posted to this list are solely the opinion of the authors, and do not represent the opinion of ACIPC.

    Archive of all messages are available at http://aicalist.org.au/archives – registration and login required.

    Replies to this message will be directed back to the list. To create a new message send an email to aicalist@aicalist.org.au

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    kkh

    ________________________________

    The information contained in this e-mail and the attachments (if any) may be privileged and confidential and is intended solely for the named addressee. If you are not the intended recipient, please do not print, retain copy, disseminate, distribute, or use this e-mail or any part thereof. Please notify the sender immediately by replying to this e-mail and delete all copies of this e-mail and the attachments.

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