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Multi-dose PET infusion system with shared IV line for multiple patients

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  • #73463
    Daniela Karanfilovska
    Participant

    Author:
    Daniela Karanfilovska

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    Dear all,

    Has anyone reviewed automated PET infusion delivery systems?

    The basic design includes:

    * a multi-dose vial of F-FDG (the radiopharmaceutical)

    * a multi-patient/shared IV administration line

    * a single-use patient administration line with a one-way valve to prevent backflow.

    At the start of the day, the shared administration line is used to access a bag of saline and the multi-dose vial; these are loaded in to a cart and covered. The administration line has a valve which protrudes from the cart which is swabbed and a single-use patient IV administration line is attached for each new patient coming in that day. Typically this is 8-9 patients in a session.

    The single-use patient administration line has a one-way check valve which prevent backflow and contamination of the same shared administration line/F-FDG which remains in use across multiple patients throughout the day.

    Our Nuclear Medicine department is interested in using this technology (as it reduces occupational exposure to F-FDG) but we have some concerns about the safety of the valve in preventing infection between patients. I have found one small in vitro study which suggests that it is safe.

    If anyone has any feedback on reviewing or using these machines (positive or negative), I would love to hear from you.

    Many thanks,
    Daniela

    Daniela Karanfilovska
    Clinical Nurse Consultant
    Infection Prevention & Healthcare Epidemiology

    t 03 90762819 m 0427 703769
    e D.Karanfilovska@alfred.org.au

    Alfred Health
    55 Commercial Road
    Melbourne VIC 3004
    PO Box 315 Prahran
    VIC 3181 Australia
    [cid:image001.jpg@01D23069.9441B840]
    Alfred Health incorporates The Alfred, Caulfield Hospital and Sandringham Hospital
    http://www.alfredhealth.org.au

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    #73479
    Matthew, John
    Participant

    Author:
    Matthew, John

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    Hi Daniela:

    Apologies for the delay in responding, just saw your mail.

    I am declaring a vested interest as my employer manufactures products that may be relevant to your enquiry.

    The Infusion Nurses Society Infusion Therapy Standards of Practice 2016 should be able to provide some guidance on what to do, as may the AVATAR group from Griffiths Uni in QLD (http://www.avatargroup.org.au/). Your hospital may already have a copy of this document (INS Infusion Therapy Standards of Practice 2016), but just in case, here is a link to their site: https://www.ins1.org/Store/ProductDetails.aspx?productId113266

    One option may be to insert an inline IV filter (0.2 m, endotoxin- and/or bacterial-retentive) with each single-use patient IV administration set. The filter is typically the last device before the patient hub/port. This will ensure that should there be a failure in the check-valve, any contamination from the patient will remain on the patient/downstream-side of the filter, and any contamination introduced into the line from upstream will remain on the upstream side of the filter.

    Your F-FDG drug manufacturer should be able to advise you on whether filters may be used with their product; your Clinical Products Advisor (Karen Flett) and Procurement Manager (Trish Jaksic) should be able to advise you on which IV filter manufacturer your hospital currently uses, and the filter manufacturer should be able to inform you whether or not F-FDG may be used with their filter.

    Thanks, and regards

    John Matthew
    Marketing & Strategic Leader
    Pall Medical, ANZ
    M: +61 419 130 668
    E: john_matthew@pall.com
    W: http://www.pall.com

    [cid:image003.png@01D23F57.15E883F0]

    Dear all,

    Has anyone reviewed automated PET infusion delivery systems?

    The basic design includes:

    a multi-dose vial of F-FDG (the radiopharmaceutical)

    a multi-patient/shared IV administration line

    a single-use patient administration line with a one-way valve to prevent backflow.

    At the start of the day, the shared administration line is used to access a bag of saline and the multi-dose vial; these are loaded in to a cart and covered. The administration line has a valve which protrudes from the cart which is swabbed and a single-use patient IV administration line is attached for each new patient coming in that day. Typically this is 8-9 patients in a session.

    The single-use patient administration line has a one-way check valve which prevent backflow and contamination of the same shared administration line/F-FDG which remains in use across multiple patients throughout the day.

    Our Nuclear Medicine department is interested in using this technology (as it reduces occupational exposure to F-FDG) but we have some concerns about the safety of the valve in preventing infection between patients. I have found one small in vitro study which suggests that it is safe.

    If anyone has any feedback on reviewing or using these machines (positive or negative), I would love to hear from you.

    Many thanks,
    Daniela

    Daniela Karanfilovska
    Clinical Nurse Consultant
    Infection Prevention & Healthcare Epidemiology

    t 03 90762819 m 0427 703769
    e D.Karanfilovska@alfred.org.au

    Alfred Health
    55 Commercial Road
    Melbourne VIC 3004
    PO Box 315 Prahran
    VIC 3181 Australia
    [cid:image001.jpg@01D23069.9441B840]
    Alfred Health incorporates The Alfred, Caulfield Hospital and Sandringham Hospital
    http://www.alfredhealth.org.au

    CONFIDENTIALITY NOTICE: This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom it is addressed. If you have received this email in error, please notify us by return email and delete all copies in your system. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or taking any action in reliance on the contents of this information is strictly prohibited and may be unlawful. Alfred Health is not liable for the proper and complete transmission of the information contained in this communication or for any delay in its receipt.
    MESSAGES POSTED TO THIS LIST ARE SOLELY THE OPINION OF THE AUTHOR, AND DO NOT REPRESENT THE OPINION OF ACIPC.

    The use of trade/product/commercial brand names through the list is discouraged by ACIPC. If you wish to discuss specific reference to products or services by brand or commercial names, please do this outside the list.

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