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Re: Nasal Decolonisation

#74067 Quote
Glenys Harrington
Participant

Author:
Glenys Harrington

Email:
infexion@ozemail.com.au

Organisation:
Infection Control Consultancy (ICC)

State:

Hi All,

For those following this thread the following information is available and
in the public domain.

The two main reference in the IC Today article that relate to the use of the
nasal antiseptic (Nozin) for decolonisation of staff and patients are as
follows:

. SteedLL et al. Reduction of nasal Staphylococcus aureus carriage
in health care professionals by treatment with a nonantibiotic,
alcohol-based nasal antiseptic. American Journal of Infection Control 42
(2014) 841-6

Full paper – http://www.ajicjournal.org/article/S0196-6553(14)00651-8/pdf

. Perioperative participation of orthopedic patients and surgical
staff in a nasal decolonization intervention to reduce Staphylococcus spp
surgical site infections. Am
J Infect Control. 2017 May 1;45(5):554-556

Full paper – http://www.ajicjournal.org/article/S0196-6553(17)30006-8/pdf

and hence should be read with caution – see link

http://www.infectioncontroltoday.com/~/media/Files/Medical/Whitepapers/2017/
10/20170922-ND-broadening-application-CP-.pdf

From the manufacturer/supplier web page:

. The product is FDA approved (OTC Drug Regulation) and it contains
the following ingredients:

. Ingredients for Nozin Nasal Sanitizer antiseptic

. Active Ingredients:
Alcohol (62% antiseptic)

. Inactive Ingredients:
jojoba, orange oil, coconut oil, lauric acid, benzalkonium chloride, vitamin
E

https://www.nozin.com/

Regards

Glenys

Glenys Harrington

Infection Control Consultancy (ICC)

P.O. Box 6385

Melbourne

Australia, 3004

M: +61 404816434

E: infexion@ozemail.com.au

Of Cathryn Murphy

Hi Matthias

I was loathe to use trade names on this site. However, I will to respond.
There is a growing body of US evidence around a product called Nozin. More
details are at nozinpro.com

When I was at APIC in June 2017 there was a lot of interest in the product
in healthcare and other settings.

Thanks for your view on the existing literature Matthias, I always enjoy
your responses.

Yours sincerely

Cath

Cathryn Murphy RN B. Photog MPH PhD CIC

Chief Executive Officer & Creative Director

Infection Control Plus Pty Ltd

QLD, Australia

E: Cath@infectioncontrolplus.com.au

M: +61 428 154154

W:http://www.infectioncontrolplus.com.au

Of Matthias Maiwald (SingHealth – PATH)

Hi Cath, hi Michael,

I am curious about the remark below concerning ethanol for nasal
decolonisation. The last time I looked (which is a while ago), the results
achieved were not convincing.

From a physiological and/or conceptual point of view, while alcohol is a
fantastic antiseptic/disinfectant for superficial skin, it is usually deemed
unsuitable for mucous membranes (which the inside of the nose consists of),
due to its more aggressive nature than aqueous antiseptics.

Best regards, Matthias.

Matthias Maiwald, MD, FRCPA

Senior Consultant in Microbiology

Adj. Assoc. Prof., Natl. Univ. Singapore

Department of Pathology and Laboratory Medicine

KK Women’s and Children’s Hospital

100 Bukit Timah Road

Singapore 229899

Tel. +65 6394 8725 (Office)

Tel. +65 6394 1389 (Laboratory)

Fax +65 6394 1387

Of Michael Wishart

Hi Cath

Just a comment: the povidone iodine nasal cream commonly used pre-op in the
US is not yet available in Australia, as far as I am aware. I wish it was,
as getting traditional pre-admission nasal decolonisation (5 days of
mupuricin or the like) done in a private hospital is not easy!

Cheers

Michael

Michael Wishart

Infection Control Coordinator

A 627 Rode Road, Chermside QLD 4032
P (07) 3326 3068 | F (07) 3607 2226 | E
michael.wishart@svha.org.au | W
http://www.hsnph.org.au
cid:image001.png@01D01926.61F1C2B0

P Please consider the environment before printing this email

Of Cathryn Murphy

Dear All

I am interested in learning more about the adoption and use of nasal
decolonisation in Australia and New Zealand. In the US this appears to be
being used sometimes in place of Contact Precautions. There is a download
from IC Today to that effect plus some recent papers. Happy to share if
anyone wants it, please email me. So would any of you be able to comment on
these questions and if and how you use nasal decolonisation in your
organisations please. Thanks in advance.

a) other than ethanol and povidone iodine (e.g.: 3M and others) what else is
used for nasal decolonisation right before surgery?

b) which are the most commonly used products?

c) what are the surgery profiles where these are used? (e.g.: ortho, open
heart, hernia repair etc)

d) what is the adoption rate for using something like this? Is it universal
or a % of surgeons opt to do it?

Yours sincerely

Cath

Cathryn Murphy RN B. Photog MPH PhD CIC

Chief Executive Officer & Creative Director

Infection Control Plus Pty Ltd

QLD, Australia

E: Cath@infectioncontrolplus.com.au

M: +61 428 154154

W:http://www.infectioncontrolplus.com.au

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