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Re: Alcohol based 2% Chlorhexidine wipe for skin disinfection

Home Forums Infexion Connexion Alcohol based 2% Chlorhexidine wipe for skin disinfection Re: Alcohol based 2% Chlorhexidine wipe for skin disinfection

#70996
HO Yuk-yin
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Author:
HO Yuk-yin

Email:
hoyy2@HA.ORG.HK

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Dear Matthias,

Thanks for your advice.

Sterile Alcohol wipe is common in my hospital for injection, venous puncture or IV ports access. Recently, we review and consider to introduce wipe of 2% chlorhexidine and 70% v/v isopropyl alcohol for IV peripheral line insertion. We found that the products available in the market is not sterile because chlorhexidine cannot undergo sterilization. Since it is not “sterile”, I have hesitation if it can also be used to disinfect IV ports or diaphragm of blood culture bottles.

Regards,
Ho Yuk Yin, APN/ICN
Infection Control Unit,
Tung Wah Hospital

Dear Ms/Mr Ho,

It can be used, provided that:

(a) the alcohol is in a sufficient concentration (at least 70% v/v ethanol or isopropanol would be required), and

(b) the alcohol wipes have been manufactured in a way that this excludes bacterial spore contamination.

Please note that for the purposes you describe, i.e. (i) to disinfect injection ports, and (ii) the diaphragms of blood culture bottles, the alcohol is the important component, not the chlorhexidine. For both purposes, alcohol wipes/swabs alone without the chlorhexidine would be sufficient.

The reason why bacterial spores need to be excluded is that the alcohol does not kill spores (actually none of the common antiseptics kills spores, also chlorhexidine does not), and this has to be taken care of during the manufacturing process. It helps if the swabs/wipes are specifically labelled as “sterile”, otherwise you may want to contact the manufacturer for further information.

Best regards, Matthias.


Matthias Maiwald, MD, FRCPA
Consultant in Microbiology
Adj. Assoc. Prof., Natl. Univ. Singapore
Department of Pathology and Laboratory Medicine
KK Women’s and Children’s Hospital
100 Bukit Timah Road
Singapore 229899
Tel. +65 6394 8725 (Office)
Tel. +65 6394 1389 (Laboratory)
Fax +65 6394 1387

Dear All,

I wonder if antiseptic wipe ” alcohol based 2% Chlorhexidine” that indicated for skin disinfection can be used to disinfect injection ports or diaphragm of blood culture bottles. Please advise.

Regards,
Ho Yuk Yin, APN/ICN
Infection Control Unit
Tung Wah Hospital

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